栄研スタッフによる解説論文集 資料　作成日　98/01/21
	Interaction between quercetin and superoxide radicals. reduction of the quercetin mutagenicity
	著者: Ueno, I., Kohno, M., Haraikawa, K. and Hirono, I.
	出典: J. Pharm. Dyn, 7, 798 -803 (1984)

要約

Interaction between quercetin and superoxide radicals was investigated using xanthine-xanthine oxidase system and potassium superoxide as superoxide radical generators. Superoxide radical scavenging action of quercetin was demonstrated by measurement of the electron spin resonance spectrum of the 5-hydroperoxy-2,2-dirnethyl-1-lpyrrolidinyloxyl adduct. Degradation of quercetin by the radicals was demonstrated spectrophotometrically. Reduction of the quercetin mutagenicity by the radicals was demonstrated in the Salmonella typhimurium strain TA 98 by the Ames test.

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