栄研スタッフによる解説論文集 資料　作成日　98/02/03
	Inhibition of platelet aggregation by some flavonoid
	著者: Tzeng, S. H., Ko, W. C., Ko, F. N. and Teng, C. M.
	出典: Thrombo. Res, 64, 91 -100(1991)

要約

The inhibitory effects of five flavonoids on the aggregation and secretion of platelets were studied. These flavonoids inhibited markedly platelet aggregation and ATP release of rabbit platelets induced by arachidonic acid or collagen, and slightly those by platelet-activating factor. ADP-induced platelet aggregation was also suppressed by myricetin, fisetin and quercetin. The IC5O on arachidonic acid-induced platelet aggregation was: fisetin, 22μM; kaempferol, 20 μM; quercetin, 13 μM; morin, 150 μM

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