栄研スタッフによる解説論文集 資料　作成日　98/02/03
	Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the netherlands
	著者: Hertog, M. G. L., Hollman, P. C. H., Katan, M. B., and Kromhout, D.
	出典: Nutr. Cancer,20,21-29(1993)

要約

Flavonoids are strong antioxidants that occur narurally in foods and can inhibit carcinogenesis in rodents. Accurate data on population-wide intakes of flavonoids are not available. Here, using data of the Dutch National Food Consumption Survey 1987-1988, we report the intake of the potentially anticarcinogenic flavonoids quercetin, kaempferol, myricetin, apigenin, and luteolin among 4112 adults. The flavonoid content of vegetables, fruits, and beverages was determined by high-performance liquid chromatography. In all subjects, average intake of all flavonoids combined was 23 mg/day. The most important flavonoid was the flavonol quercetin (mean intake 16 mg/day). The most important sources of flavonoids were tea (48% of total intake), onions (29%). and apples (7%). Flavonoid intake did not vary between seasons; it was not correlated with total energy intake (r= 0.001), and it was only weakly correlated with the intake of vitamin A (retinol equivalents, r= 0.14), dietary fiber (r=0.21), and vitamin C (r= 0.26). Our use of new analytic technology suggests that in the past flavonoid intake has been overestimated fivefold. However, on a milligram-per-day basis, the intake of the antioxidant flavonoids still exceeded that of the antioxidants β-carotene and vitamin E. Thus flavonoids represent an important source of　antioxidants in the human diet.

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